Albendazole is a broad-spectrum antihelminthic medication commonly used to treat worm infections in humans. It is highly effective against various types of intestinal worms, including roundworms, hookworms, whipworms, and certain tapeworms. Albendazole 400 mg works by interfering with the energy metabolism of the parasites, specifically by inhibiting the polymerization of tubulin, which is essential for their cellular structure and function. This disruption prevents the worms from absorbing glucose, ultimately leading to their death. The medication is usually administered orally, often as a single dose for most intestinal worm infections, though longer courses may be required for severe or persistent infections. Albendazole is widely used in both individual treatments and mass deworming programs, particularly in regions with high prevalence of parasitic infections. It is generally well-tolerated, with side effects being mild and temporary, such as nausea, abdominal pain, or headache. However, it should be used with caution in pregnant women, especially during the first trimester, and under medical supervision in individuals with liver disease. Overall, albendazole remains a safe, effective, and essential treatment for controlling worm infections in humans, reducing morbidity, improving nutrition, and preventing long-term complications associated with parasitic infestations.